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NCBI Datasets

Science Data No key

AuthenticationNo key
Rate limitNo published quota; follow NCBI's courtesy guidance of about 3 requests per second.

Documentation: www.ncbi.nlm.nih.gov ยท Checked Sep 13, 2026

About

NCBI Datasets is the National Center for Biotechnology Information's tool for grabbing genomic data in bulk. You can download entire genomes, gene sequences, and annotation packages by species name or accession number. It is free with no key, and works through a simple command-line tool or a REST API.

Details

No key needed. You can call it right away.

Auth: No key

Rate limit: No published quota; follow NCBI's courtesy guidance of about 3 requests per second.

Verified: 2026-09-13

Best for: developer personal

Setup

  1. Install the free datasets command-line tool following the download-and-install docs.
  2. Run the example command to download human genomes into a zip package.
  3. Swap human for any species name or use an assembly accession like GCF_000001405.40.
  4. For code-based use, call the REST API at https://api.ncbi.nlm.nih.gov/datasets/v2/ with the same filters.