NCBI Datasets
Science Data No key
AuthenticationNo key
Rate limitNo published quota; follow NCBI's courtesy guidance of about 3 requests per second.
Documentation: www.ncbi.nlm.nih.gov ยท Checked Sep 13, 2026
About
NCBI Datasets is the National Center for Biotechnology Information's tool for grabbing genomic data in bulk. You can download entire genomes, gene sequences, and annotation packages by species name or accession number. It is free with no key, and works through a simple command-line tool or a REST API.
Details
No key needed. You can call it right away.
Auth: No key
Rate limit: No published quota; follow NCBI's courtesy guidance of about 3 requests per second.
Verified: 2026-09-13
Best for: developer personal
Setup
- Install the free datasets command-line tool following the download-and-install docs.
- Run the example command to download human genomes into a zip package.
- Swap human for any species name or use an assembly accession like GCF_000001405.40.
- For code-based use, call the REST API at https://api.ncbi.nlm.nih.gov/datasets/v2/ with the same filters.
Example
datasets download genome taxon human --filename human_dataset.zipUse cases
- Download the complete human reference genome for a bioinformatics class
- Pull all genomes for a species by name for a comparative study
- Get gene sequences and protein data for a gene ID in one package